The effect of dexamethasone on post-tonsillectomy nausea, vomiting and bleeding.
نویسندگان
چکیده
UNLABELLED It has been stated, that the administration of Dexamethasone has an impact on the morbidity following tonsillectomy. OBJECTIVE To re-calculate the blood values for Dexamethasone when given as fixed doses and to evaluate the effect of Dexamethasone on post-operative nausea, vomiting and bleeding rates following tonsillectomy. MATERIALS AND METHODS The charts of 272 children (2-15 years) who had undergone tonsillectomy were analyzed. The rates of post-operative nausea, vomiting and bleeding in relation to Dexamethasone were calculated-in general and different doses (0 mg/kg, <0.15 mg/kg, >0.15 mg/kg). STUDY DESIGN Retrospective cohort study. RESULTS Dexamethasone was administered in 121 children (43.7%) according to the preference of the anesthesist (mean dose: 0.2 +/- 0.12 mg/kg; range: 0.04 - 0.62 mg/kg). There was no significant difference in nausea and vomiting (p=0.953) or bleeding (p=0.827) across groups receiving or not receiving Dexamethasone. Stratification into three different groups of Dexamethasone concentration also did not identify a dose-related risk of postoperative nausea or vomiting (p=0.98) or bleeding (p=0.71). CONCLUSION At least under common non-controlled conditions in the clinic, Dexamethasone does not appear to have an effect on nausea or vomiting or bleeding following tonsillectomy.
منابع مشابه
Preemptive Dexamethasone Reduces Pediatric Post-Tonsillectomy Pain: A Triple-Blind Randomized Clinical Trial
Background and Objective: Adenotonsillectomy is one of the most commonly performed surgical procedures in children. Although this surgery is technically easy, it can run a high risk of serious complications, such as laryngeal spasm, laryngitis, bleeding, pain, and nausea. The present study aimed to assess the effect of preemptive dexamethasone on pediatric post tonsillectomy pain. Materials a...
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ورودعنوان ژورنال:
- Brazilian journal of otorhinolaryngology
دوره 77 3 شماره
صفحات -
تاریخ انتشار 2011